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It would be valuable to investigate the distinct functions of DUSPs in various tissues of inflammatory and chronic diseases using tissue-specific KO animals

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While TPI is commonly used for fibromyalgia, it can also be beneficial for treating other conditions, such as muscle strains, myofascial pain syndrome , and tension headaches

All analyses were conducted using a 1260 Agilent Technologies system (Agilent Technologies Inc., Santa Clara, CA, USA) equipped with a binary pump and vacuum degasser, and a Varian 410 Prostar autosampler (Varian Inc., Palo Alto, CA, USA) with a 10 L injection loop